Shahid Afridi and Umar Akmal were the most notable absentees as Pakistan confirmed their 15-man squad for June's Champions Trophy.
All-rounder Afridi, an explosive hitter and a big character, will be missed by crowds in England and Wales this summer but was not deemed to have performed well enough on the recent tour of South Africa. Shoaib Malik is retained in his place.
Umar, meanwhile, has long been considered one of Pakistan's biggest talents, though has yet to deliver consistently at the highest level. His older brother Kamran is selected as the specialist wicketkeeper, while Umar Amin travels as the spare batsman.
Misbah-ul-Haq continues as captain while the bowling ranks look strong despite the injury-enforced absence of Umar Gul. Junaid Khan, Mohammad Irfan, Wahab Riaz and spinner Saeed Ajmal all have pedigree, though Sohail Tanvir misses out in favour of Ehsan Adil and Asad Ali.
The squad also covers four one-day matches against Ireland and Scotland.
Meanwhile, Pakistan have appointed the Australian Trent Woodhill as their batting coach for the Champions Trophy.
Pakistan squad: Misbah ul Haq (captain), Mohammad Hafeez, Imran Farhat, Nasir Jamshed, Kamran Akmal (wicketkeeper), Shoaib Malik, Asad Shafiq, Saeed Ajmal, Junaid Khan, Mohammad Irfan, Asad Ali, Wahab Riaz, Umar Amin, Abdur Rehman, Ehsan Adil.