Stephen George compiled his maiden ODI century as England Deaf got their tour of South Africa off to the perfect start with a 60-run win in Pretoria.
George compiled exactly 100 in a total of 273 for six that also featured 56 from skipper Umesh Valjee, who won the toss.
South Africa were then limited to 213 in reply, Michael Weathersby returning 4-31 and George Greenway 3-27.
After Valjee had called correctly, England`s openers progressed comfortably in a valuable stand of 115.
Valjee eventually departed to the spin of Avinash Kallichuran and James Schofield made only six before falling lbw for six to Shamiel Howley.
Yet George pressed on and looked to accelerate in the company of Greenway, whose 32 spanned just 28 deliveries.
Paul Allen continued the momentum and added a brisk 28 before a misunderstanding led to the middle-order batsman being run out.
George duly brought up his hundred off 116 balls with a straight-driven two. His innings of real maturity lasted a shade over three hours but was ended immediately when he fell lbw to the 116th ball he faced.
Weathersby finished unbeaten on 28 not out and Darrell Sykes subsequently gave England a boost by having Charl Bonthuys caught at first slip in the fifth over of South Africa`s reply.
A fifty stand between Rishaad Shaik and wicketkeeper Eric Minaar came to an end when the former was bowled by Greenway for 26.
Two further wickets fell in quick succession to leave South Africa in trouble at 88 for four but Reinhardt Limbacht then shared 84 - the highest alliance of the innings - with skipper Rual Kumalo.
It was Weathersby who broke the partnership by inducing a mis-timed drive to Valjee at mid-off from Limbacht.
South Africa were left requiring 100 from the final 10 overs and lost wickets on a regular basis as they tried in vain to increase the tempo.
The win puts England 1-0 up in the four match series. The second game is due to take place on Friday at the same venue.