Durham's hopes of boosting their title challenge with a win at Derby were frustrated by a combination of accurate Derbyshire bowling and bad weather on the third day of the LV= County Championship match.
The Division One leaders have never won a championship game at the County Ground and their chances of ending that run appear to be fading after they closed 41 runs behind on 257 for four when rain ended play early.
Scott Borthwick and and Will Smith, with 89 and 81 respectively, shared a third-wicket stand of 159 in 62 overs but Derbyshire kept them in check and the game now looks to be heading for a draw.
Durham had to score quickly to get in a position where they could put Derbyshire under pressure yet Borthwick and Smith found it hard to get the ball away on a slow pitch against disciplined bowling.
With their Division One status on the line, Derbyshire needed the bowling points and were unlucky not to pick up several wickets during a morning session in which only 88 runs were scored in 31 overs.
Both batsmen played and missed a number of times but maintained their concentration to slowly edge Durham towards Derbyshire's 298.
When Borthwick got to 44, he became the first homegrown Durham batsman to score 1,000 first-class runs for the county since 2005; however, the fact his fifty contained only five fours showed how well Derbyshire had bowled.
Smith needed 125 balls to reach his half-century and any plans Durham had of raising the tempo after lunch were frustrated by more accurate seam and spin bowling.
Tony Palladino and David Wainwright conceded only 13 runs in 11 overs and the pressure told when Shivnarine Chanderpaul snared Borthwick with his occasional leg-spin.
Borthwick had scored 89 in four hours when he tried to dispatch a full-toss for his eighth four and was caught low down by Tim Groenewald at mid-on.
With Wainwright conceding only 19 runs in 14 overs, Derbyshire delayed taking the second new ball.
Yet when they did claim it, Mark Footitt removed Smith with a rapid ball that the batsman edged to second slip as he tried to take his bat away.
Paul Collingwood passed 13,000 first-class runs before rain washed out the last 21 overs.