Former Durham and Northamptonshire batsman Kyle Coetzer will captain Scotland for the one-off ODI against England on Sunday.
Coetzer, who has Hampshire seamer Brad Wheal to call upon, will be hoping to register Scotland's first win over England.
The teams have met four times with England winning three and one no-result in 2008.
The match at the Grange, which is sold out, is live on Sky.
Scotland squad to face England:
Kyle Coetzer (captain)
Richie Berrington (vice-captain)